CPHS Logo
Committee for the Protection of Human Subjects

CPHS Announcement

CPHS will be launching its new system, IRBManager, on Friday, September 1, 2017. Due to CPHS’ transition to IRBManager, starting August 3, 2017, CPHS will not be accepting applications entered into CalPROTECTS. Projects entered on or after August 3, 2017, will need to be re-entered by the Researcher on IRBManager.

The revised submittal due date for all applications is extended to Wednesday, September 13, 2017.

IRB Manager will be available to all researchers and staff on Friday, September 1, 2017. We are looking forward to utilizing IRBManager. We apologize for any inconvenience this may cause you. If you have any questions, you may contact CPHS by email at cphs-mail@oshpd.ca.gov or by calling (916) 326-3660.

Mission and Purpose

The Committee for the Protection of Human Subjects (CPHS) serves as the institutional review board (IRB) for the California Health and Human Services Agency (CHHSA). The role of the CPHS and other IRBs is to assure that research involving human subjects is conducted ethically and with minimum risk to participants.

Ethical Principles

The CPHS is guided by principles delineated in the Belmont Report, which was issued by the U.S. Department of Health, Education, and Welfare in April 1979. These principles include:

Respect for Persons

"Respect for persons incorporates at least two ethical convictions: first, that individuals should be treated as autonomous agents, and second, that persons with diminished autonomy are entitled to protection. The principle of respect for persons thus divides into two separate moral requirements: the requirement to acknowledge autonomy and the requirement to protect those with diminished autonomy."

Beneficence

"Persons are treated in an ethical manner not only by respecting their decisions and protecting them from harm, but also by making efforts to secure their well-being. Two general rules have been formulated as complementary expressions of beneficent actions in this sense: (1) do not harm and (2) maximize possible benefits and minimize possible harms."

Justice

".the selection of research subjects needs to be scrutinized in order to determine whether some classes (e.g., welfare patients, particular racial and ethnic minorities, or persons confined to institutions) are being systematically selected simply because of their easy availability, their compromised position, or their manipulability, rather than for reasons directly related to the problem being studied. Finally, whenever research supported by public funds leads to the development of therapeutic devices and procedures, justice demands both that these not provide advantages only to those who can afford them and that such research should not unduly involve persons from groups unlikely to be among the beneficiaries of subsequent applications of the research."


This page was last updated on Thursday, August 3, 2017.